Oncology

A global solution, from sample to result

Based on its expertise in molecular biology, from nucleic acid extraction to digital PCR, ID SOLUTIONS develops and offers a range of products dedicated to oncology.

ID SOLUTIONS ONCOLOGY kits provide :

Qualification and/or quantification of each sample

Normalization of circulating DNA concentration

Detection of cancer-specific mutations

Based on dPCR : detection of several molecular alterations in a single well
Incorporate sample qualification and/or quantification controls. ICE = Internal Control of Extraction: patent FR3061720/ WO2018…
Suitable for analysis of free circulating DNA or tissue DNA
Offer sensitive, specific, standardizedresults to meet today’s needs and requirements.

dPCR reagents

IDESR1+

Detection system for ESR1 activating mutations on Exon 8 and the E380Q mutation

IDEGFR-SENSI

Multiplex EGFR mutation detection system (L858R, L861Q, Del19)

IDEGFR-RESIST

Multiplex EGFR mutation detection system (T790M, C797S)

IDEGFR-RARE

Multiplex EGFR mutation detection system (S768I, G719X, ins20)

oSolutions EGFR 4 Exons mutations (Sr)

Système de détection qualitatif par PCR digitale de
mutations présentes sur les exons 18, 20 et 21 et de
délétions sur l’exon 19 de l’EGFR

IDKRAS

Multiplex KRAS mutation detection system (G12-G13, Q61)

IDKRAS-3X

Multiplex system for detecting mutations in exon 2 (variants G12X and G13X), exon 3 (variants Q61X) and exon 4 (variants A146X and K117)

IDKRAS-G12C

Multiplex KRAS mutation detection system (G12C)

IDNRAS

Multiplex NRAS mutation detection system (G12-G13, Q61)

IDBRAF

Multiplex BRAF mutation detection system (L597, A598, V600, K601)

IDBRAF-CNS

Multiplex detection system for BRAF V600E mutation and KIAA1546-BRAF fusion

IDPIK3CA

Multiplex detection system for PIK3CA mutations (E542/5K, H1057R/L, Q546K)

IDIDH1-2

Multiplex IDH1-2 mutation detection system (R132X, R172X)

IDIDH1-2 + R140X

Multiplex IDH1-2 mutation detection system (R132X, R172X, R140X)

IDH3F3A

Multiplex detection system for H3F3A mutations (K27M, G34V, G34R)

IDTERT

Multiplex TERT mutation detection system (C228T, C250T)

IDFGFR1-CNS

Multiplex detection system for FGFR1 mutations and tandem duplication of exons 11 to 18

IDmMLH1

Quantification du taux de méthylation du promoteur de MLH1

Multiplexed solutions / Quality control / Validation data Validation data

Speed

Results in less 24h

Ready to use

Suitable for FFPE and plasma samples

High specificity and sensitivity

Up to 1% in FFPE and 0.1% in plasma

Quality controls included

Standardization and normalization of results

High compatibility

Compatible with market-leading dPCR instruments

A simplified digital PCR workflow

Only when using research reagents

Extraction

Step 1 :
DNA isolation from tissue or plasma*

Qualification quantification

Step 2 :
Standardization*

Deposit

Step 3 :
Sample + Mix*

Partition

Step 4 :
DNA partitioning

Amplification

Etape 5 :
Amplification and detection

Analysis

Step 6 :
Results analysis

*Possible automation

DNA extraction kits optimized for plasma and FFPE samples

A solution for your tumor DNA extractions

Optimisez vos analyses en oncologie avec nos kits d’extraction haute performance !
Conçus pour garantir pureté, rendement et fiabilité, ils assurent des résultats précis et reproductibles.

“Method for detection and quantification of circulating DNA and uses” PATENTED TECHNOLOGY

Official publication numbers of “FR3061720” / “WO2018/127674” applications

IDQUANT, kit for quantifying and normalizing circulating DNA by qPCR or digital PCR (dPCR)

The IDQUANT kit enables standardized monitoring of circulating DNA over time, thanks to our internal control (ICE).

The kit contains a Target Positive Control (TPC) for validation from extraction to amplification.

Sample qualification / Standardized quantification