IDNAPTEX mMLH1 enables accurate detection and quantification of MLH1 promoter methylation using an optimized mix of primers and fluorescent probes specifically designed for digital PCR (dPCR) analysis.
Methylation of the MLH1 gene promoter is a mechanism of functional inactivation (of the promoter) leading to the cessation of MLH1 protein synthesis and a deficiency in the DNA repair system.
Based on ICE* technology developed by ID SOLUTIONS, IDNAPTEX mMLH1 ensures high sensitivity, precise quantification, and excellent reproducibility, even when working with challenging clinical samples such as FFPE tissues (gDNA).
Reagents are supplied in pre-mixed tubes, with primers and probes ready to use, simplifying workflow, reducing handling steps, and ensuring optimal standardization for routine laboratory use.
