IDONTRAX ESR1 kit is a high-precision molecular diagnostic solution designed for the simultaneous identification of mutations in the ESR1 gene and wild-type alleles.
Thanks to an optimised formulation of primers and fluorescent probes, this test enables precise discrimination between resistance variants, which is essential for guiding treatment.
The system detects and differentiates between critical mutations distributed across the functional domains of the receptor:
Exon 5: E380Q, Exon 8: L536H, L536P, L536R, L536Q, L536F, Y537S, Y537C, Y537N, Y537D, Y537H and D538G, Exon 7: S463P, Exon 6: V422del
Featuring ICE* technology developed by ID SOLUTIONS, IDONTRAX ESR1 offers high sensitivity and reproducibility. This proprietary technology ensures reliable results, whether you are working with circulating DNA (cfDNA) from plasma or genomic DNA (gDNA) extracted from FFPE tissue.
*Not included in the kit.
